Copper-catalyzed addition of H-phosphine oxides to alkynes forming alkenylphosphine oxides.
نویسندگان
چکیده
We have developed efficient copper-catalyzed additions of P(O)H compounds to alkynes, and the reactions provided the regio- and stereoselective E-alkenylphosphine oxides under catalysis of the commercially available and inexpensive copper catalyst system CuI/ethylenediamine. This finding is the first example of copper-catalyzed hydrophosphinylation of alkynes to synthesize alkenylphosphine oxides.
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ورودعنوان ژورنال:
- Chemical communications
دوره 3 شماره
صفحات -
تاریخ انتشار 2007